Michael J. Moore, MD
To the Editor: The recent article by Fraser and Arieff (1) is very well written and provides helpful information concerning the pathophysiology involved in hyponatremia. However, I read this article with dismay and sadness as I thought about the many who died because of the trend to use hypotonic solutions for intravenous fluid therapy. I became aware of this trend about 6 years ago and questioned younger surgeons and anesthesiologists about how it had developed. It appears that university hospital anesthesiologists were aware of a tendency of surgical patients having anesthesia to retain sodium, and hypotonic infusions were thought to
Moore MJ. Overuse of Hypotonic Fluids. Ann Intern Med. 1990;112:716–717. doi: 10.7326/0003-4819-112-9-716_2
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Published: Ann Intern Med. 1990;112(9):716-717.
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