Paul S. Kellerman, MD; Stuart L. Linas, MD
Ascites occurs in most patients with severe cirrhosis. Although the presence of ascites is often obvious, smaller amounts of ascitic fluid can be difficult to diagnose. Ultrasonography has been helpful in diagnosing the presence and determining the cause of ascites (1). Hepatic outflow obstruction is central to ascites formation. Of continued debate is whether ascites formation is a primary event resulting in relative hypovolemia and secondary renal salt retention or is secondary to primary renal sodium avidity. There is evidence supporting both the "underfill" (2, 3) and "overflow" (4) theories, and various therapies are based on correcting the abnormalities postulated
Paul S. Kellerman, Stuart L. Linas. Large-Volume Paracentesis in Treatment of Ascites. Ann Intern Med. 1990;112:889–891. doi: 10.7326/0003-4819-112-12-889
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Published: Ann Intern Med. 1990;112(12):889-891.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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