Naguib A. Samaan, MD, PhD; Frank K. Pham, BS; Rena V. Sellin, MD; Jose F. Fernandez, MD; Robert S. Benjamin, MD
The mechanism of hypoglycemia in extrapancreatic tumors remains controversial, and no treatment has been established. Some investigators have suggested that the hypoglycemia may, in part, be the result of growth-hormone deficiency and, if so, that treatment with growth hormone might be beneficial (1-3). This theory, however, has not been tested. We recently had the opportunity to evaluate both the mechanism of and the treatment options for hypoglycemia in a patient with a severe case resulting in meningeal sarcoma with retroperitoneal and liver metastases. We found that although growth-hormone deficiency was present, growth-hormone treatment was not effective; continuous intravenous glucagon administration,
Samaan NA, Pham FK, Sellin RV, Fernandez JF, Benjamin RS. Successful Treatment of Hypoglycemia Using Glucagon in a Patient with an Extrapancreatic Tumor. Ann Intern Med. ;113:404–406. doi: 10.7326/0003-4819-113-5-404
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Published: Ann Intern Med. 1990;113(5):404-406.
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