Antonio Aceti, MD; Gloria Taliani, MD
To the Editors: The detection of antibodies to hepatitis C virus (HCV) using a recombinant-based immunoassay in patients who did not have risk factors for infection or evidence of liver disease has raised doubts about the test's specificity (1).
We recently looked for antibodies to HCV (anti-HCV) in sera specimens from 76 patients with a parasitic infection (49 with surgically proved hydatidosis and 27 with parasitologically diagnosed urinary schistosomiasis), none of whom had a history of blood contacts. Antibody to HCV was tested for using an enzyme-linked immunosorbent assay (ELISA) (Ortho Diagnostic Systems, Raritan, New Jersey). The test was carried
Aceti A, Taliani G. Hepatitis C Virus Antibodies in Parasitic Infections. Ann Intern Med. ;113:560. doi: 10.7326/0003-4819-113-7-560_1
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Published: Ann Intern Med. 1990;113(7):560.
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