Richard G. Farmer, MD; Linda Johnson White
In our position paper on therapeutic substitution (1), we incorrectly cite cefazolin and cefotaxime as an example of therapeutic equivalents with the same pharmacokinetic and pharmacodynamic properties. The drugs are first- and third-generation cephalosporins. In reality, it is difficult to identify two drugs with exactly the same properties; the College's position paper deals with substitution of drugs with similar pharmacologic and therapeutic properties, as occurs in actual practice. We regret the error.
Farmer RG, White LJ. Correction: Therapeutic Substitution and Formulary Systems. Ann Intern Med. ;113:640. doi: 10.7326/0003-4819-113-8-640_2
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Published: Ann Intern Med. 1990;113(8):640.
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