O. D. Bruno, MD; M. A. Rossi, MD; L. N. Contreras, MD
To the Editors: In their diagnosis and treatment article, Kaye and Crapo (1) thoroughly reviewed the advances made in the diagnostic evaluation of the Cushing syndrome. They concluded that the overnight high-dose dexamethasone test (2, 3) combined with plasma adrenocorticotropin (ACTH) measurements would be the procedure of choice in the etiologic evaluation, were its utility for use in outpatients proved. They stressed, however, that the test was done in hospitalized patients in one study (2), whereas the conditions under which it was done were not stated in another study (3). To clarify that point, we (the investigators in the latter
Bruno OD, Rossi MA, Contreras LN. Diagnosis of Cushing Disease. Ann Intern Med. ;113:807. doi: 10.7326/0003-4819-113-10-807_1
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Published: Ann Intern Med. 1990;113(10):807.
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