Richard G. Appel, MD; James Neill, MD
Patients with human immunodeficiency virus (HIV) seropositivity may present with various renal abnormalities, including minimal, focal, or diffuse glomerular mesangial proliferation (1-3). In addition, they may present with the "HIV-associated nephropathy" syndrome, which is characterized by a rapid progression to end-stage renal disease (4-7). We provide evidence that therapeutic intervention is appropriate in some settings.
A 37-year-old white man developed generalized lymphadenopathy in August 1988. A lymph node biopsy revealed benign reactive hyperplasia. Urinalysis revealed 4+ protein by dipstick. In September 1988, the patient was admitted with dyspnea associated with increasing fluid accumulation. He denied intravenous drug use,
Appel RG, Neill J. A Steroid-Responsive Nephrotic Syndrome in a Patient with Human Immunodeficiency Virus (HIV) Infection. Ann Intern Med. ;113:892–893. doi: 10.7326/0003-4819-113-11-892
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Published: Ann Intern Med. 1990;113(11):892-893.
Infectious Disease, Nephrology, Nephrotic Syndrome.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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