Russell D. Hull, MBBS, MSc; Gary E. Raskob, MSc
The sensitivity and specificity of Biello's (1) and Mc-Neil's (2) widely used criteria for the diagnosis of pulmonary embolism are unknown. These classic criteria are currently the basis for categorizing lung scan findings as being of high, intermediate, or low probability (1-4).
Previous prospective studies, in which consecutive patients had pulmonary angiography, have been criticized for reporting predictive values without reporting sensitivity and specificity (5). The latter indices are independent of prevalence, whereas predictive values depend on prevalence and therefore are more influenced by the clinical setting in which the study is done. The Prospective Investigation of Pulmonary Embolism Diagnosis
Hull RD, Raskob GE. Low-Probability Lung Scan Findings: A Need for Change. Ann Intern Med. 1991;114:142–143. doi: 10.7326/0003-4819-114-2-142
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Published: Ann Intern Med. 1991;114(2):142-143.
Hospital Medicine, Neurology, Stroke.
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