Nikolai V. Naoumov, MD; Todor Lissichkov, DSc; Maria G. Rumi, MD
To the Editors: The important role of hepatitis C virus (HCV) in the cause of transfusion-associated and community-acquired hepatitis in the United States and Western Europe has recently been shown (1-3). We tested 51 Bulgarian patients (32 with congenital clotting disorders and 19 with biopsy-proven cryptogenic chronic liver diseases) for antibody to HCV (anti-HCV).
Patients with clotting defects (hemophilia A, 28 patients; hemophilia B, 2 patients; von Willebrand disease, 1 patient; factor VII deficiency, 1 patient) ranged in age from 15 to 58 years and had been treated with only locally manufactured lyophilized plasma cryoprecipitate. One series of this cryoprecipitate
Naoumov NV, Lissichkov T, Rumi MG. Hepatitis C Virus Infection in Hemophiliacs. Ann Intern Med. ;114:171–172. doi: 10.7326/0003-4819-114-2-171_2
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Published: Ann Intern Med. 1991;114(2):171-172.
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