Philip H. Frost, MD
To the Editors: Niacin (nicotinic acid) is recognized as a drug of first choice for the treatment of the hyperlipidemias (1). Niacin is produced as a dietary supplement, but it has become increasingly clear that all preparations are not the same. A dramatic example of intolerance to a "regular" niacin preparation follows.
A fifty-six-year old man was prescribed cholestyramine in February 1987 for hypercholesterolemia. In 1988, niacin was added as a second lipid-lowering agent with the dosage advanced to 1.5 g three times a day. "Crystalline Pure Niacin," dispensed in a 500-mg hard gelatin capsule (TWINLAB, Twin Laboratories, Ronkonkoma, New
Philip H. Frost. All Niacin Is Not the Same. Ann Intern Med. 1991;114:1065. doi: 10.7326/0003-4819-114-12-1065_1
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Published: Ann Intern Med. 1991;114(12):1065.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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