Mark A. Getz, MD; Ramiah Subramanian, MD; Tim Logemann, MD; Ford Ballantyne, MD
Acute necrotizing eosinophilic myocarditis is characterized by acute and fulminant congestive heart failure that has previously been uniformly fatal (1, 2). Predisposing factors include an initial viral infection and an underlying allergic diathesis. This disease's pathologic characteristics include eosinophilic and lymphocytic infiltration with extensive myocardial cell necrosis and no notable extracardiac pathologic findings. Hypersensitivity myocarditis is characterized by rash, fever, sinus tachycardia, and eosinophilia related to a drug allergy. This entity is also characterized by eosinophilic and lymphocytic infiltration of the myocardium, but necrosis is uncommon (3). Patients with hypersensitivity myocarditis usually are not critically ill, and they respond to
Getz MA, Subramanian R, Logemann T, Ballantyne F. Acute Necrotizing Eosinophilic Myocarditis as a Manifestation of Severe Hypersensitivity Myocarditis: Antemortem Diagnosis and Successful Treatment. Ann Intern Med. 1991;115:201–202. doi: 10.7326/0003-4819-115-3-201
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Published: Ann Intern Med. 1991;115(3):201-202.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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