Barbara Feuerstein, MD; David H.P. Streeten, MB, DPhil
Massive bilateral adrenal hemorrhage causing adrenal insufficiency, shock, and death has been recognized at autopsy for many years. Such hemorrhages may result from acute meningococcal and other bacterial septicemias (especially in children), thromboembolic disease, the therapeutic use of anticoagulants, surgical and other forms of "stress," and severe trauma (1-6). The autopsy results from 5 of 60 patients who died after closed thoracic, abdominal, or pelvic injuries, showed bilateral adrenal hemorrhages. Severe bilateral hemorrhages have usually been fatal if they were unrecognized and untreated (7). Adrenal insufficiency in survivors has usually been permanent and has required continued steroid-replacement therapy (4). We
Feuerstein B, Streeten DH. Recovery of Adrenal Function after Failure Resulting from Traumatic Bilateral Adrenal Hemorrhages. Ann Intern Med. 1991;115:785–786. doi: 10.7326/0003-4819-115-10-785
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Published: Ann Intern Med. 1991;115(10):785-786.
Adrenal Disorders, Endocrine and Metabolism.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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