James W. Mosley, MD; Jorge Rakela, MD
To the Editors: The failure of Wright and coworkers (1) to find specific hepatitis C virus (HCV) sequences by reverse-transcription polymerase chain reaction in 15 patients with acute hepatic failure who were referred for liver transplantation is surprising. Unfortunately, the brevity of the report makes it difficult to evaluate the applicability of their results to other series.
During the 1970s, the Acute Hepatic Failure Study Group (AHFSG) carried out two cooperative clinical trials of therapies for fulminant hepatitis at centers throughout the United States and Canada (2, 3). As new tests for etiologic agents have become available, we have repeatedly
Mosley JW, Rakela J. Hepatitis C Virus and Fulminant Hepatitis. Ann Intern Med. ;115:983–985. doi: 10.7326/0003-4819-115-12-983_2
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Published: Ann Intern Med. 1991;115(12):983-985.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease, Viral Hepatitis.
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