Stephen R. Plymate, MD; Karl E. Friedl, PhD
To the Editors: The article by Elashoff and colleagues (1) provided a comprehensive assessment of the status of our current knowledge of the possible effects of androgens on muscular strength. In addition to the numerous deficiencies of the reported studies noted by Elashoff, we point out that none of the studies provided any measurement of the steroid levels obtained in blood or tissue. This factor may result from the difficulty of measuring in serum the variety of anabolic agents taken by athletes. However, considering the multiple routes of androgen metabolism it is difficult to determine an androgen response without some
Plymate SR, Friedl KE. Anabolic Steroids and Muscle Strength. Ann Intern Med. 1992;116:270. doi: 10.7326/0003-4819-116-3-270
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Published: Ann Intern Med. 1992;116(3):270.
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