Burke A. Cunha, MD
To the Editors: Approximately 80% of patients with the chronic fatigue syndrome, as defined by the Centers for Disease Control (1-3), seen in the Winthrop-University Hospital Chronic Fatigue Syndrome Center, have a peculiar purplish discoloration of both anterior pharyngeal pillars. The crescents are an intense crimson color and are well demarcated along the margins of both anterior pharyngeal pillars. They are not associated with pharyngitis or discoloration of the posterior pharyngeal pillars or uvula or accompanied by either anterior or posterior cervical adenopathy. In patients without tonsils, the crimson crescents assume a posterior position in the oropharynx. This appearance is
Cunha BA. Crimson Crescents—A Possible Association with the Chronic Fatigue Syndrome. Ann Intern Med. ;116:347. doi: 10.7326/0003-4819-116-4-347_2
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Published: Ann Intern Med. 1992;116(4):347.
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