W. Edmund Farrar, MD
To the Editors: Human bite wounds are notoriously prone to the development of infection. The combination of trauma to tissues and deep inoculation of the abundant and varied microorganisms present in the oral cavity often tips the balance in favor of the invaders (1). Recent studies have emphasized the polymicrobial nature of these infections, from which an average of five or six bacterial species, including both aerobic and anaerobic types, is isolated (2, 3). Suppurative tenosynovitis, septic arthritis, or osteomyelitis develop in half the cases, and, before the development of antibiotics, bacteremic infections were occasionally fatal (4).
An early case
Farrar WE. "A Poisoned Tooth". Ann Intern Med. ;116:429. doi: 10.7326/0003-4819-116-5-429
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Published: Ann Intern Med. 1992;116(5):429.
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