Tsung O. Cheng, MD
To the Editors: The case reported by Adolph and colleagues (1) of orthodeoxia-platypnea caused by pericardial effusion-related right-to-left atrial shunting is unusual. Right-to-left shunting through a patent foramen ovale is usually associated with spontaneous (2) or induced (3) pulmonary hypertension. In the absence of pulmonary hypertension and, therefore, in the absence of a right-to-left pressure gradient, right-to-left atrial shunting is caused by preferential redirecting of flow from the inferior vena cava toward the patent foramen ovale.
A persistent eustachian valve can cause (in addition to pericardial effusion, which results in an anatomic distortion of the right atrium) interatrial right-to-left shunting
Tsung O. Cheng. Reversible Orthodeoxia. Ann Intern Med. 1992;116:875. doi: 10.7326/0003-4819-116-10-875_1
Download citation file:
Published: Ann Intern Med. 1992;116(10):875.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use