Joel B. Epstein, DMD, MSD; Christopher H. Sherlock, MD; Robert A. Wolber, MD
To the Editors: Oral disease frequently develops in immunosuppressed patients, and cytomegalovirus contributes to this by producing mucosal ulcers as it does elsewhere in the alimentary tract. We describe here the first reported case of cytomegalovirus gingivitis that resulted in symptomatic hyperplasia rather than in ulceration.
A 35-year-old cytomegalovirus-seronegative man received a heart transplant on 9 November 1989, from a cytomegalovirus-seropositive donor. He was immunosuppressed with cyclosporine A, azathioprine, and prednisone. In December, he developed gum enlargement and tenderness. On February 26, when a biopsy was done, his gingiva were markedly enlarged, firm, and pink, extending to the incisa edges
Epstein JB, Sherlock CH, Wolber RA. Cytomegalovirus-induced Gingivitis. Ann Intern Med. 1992;116:1034. doi: 10.7326/0003-4819-116-12-1034_1
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Published: Ann Intern Med. 1992;116(12_Part_1):1034.
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