Ken Tanigawa, MD; Shunichi Yamashita, MD; Shigenobu Nagataki, MD
To the Editors: The pathophysiology of acromegaly has been well-reviewed (1). Although enlargement is observed in soft tissue and cartilage, it is variable in bone, with a few reports of involvement of the cervical spine (2-5). We report a case of a 52-year-old Japanese man admitted for the chief symptoms of hand numbness and gait disturbance, which gradually progressed over a 2-year period to paresthesia of the hands and gait disturbance.
Physical examination and laboratory investigations showed the classic stigmata of acromegaly. On neurologic examination, there was decreased strength of the flexor carpi muscles of the right hand, hypesthesia of
Tanigawa K, Yamashita S, Nagataki S. Acute Quadriplegia in Acromegaly. Ann Intern Med. ;117:94–95. doi: 10.7326/0003-4819-117-1-94_2
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Published: Ann Intern Med. 1992;117(1):94-95.
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