Richard B. Devereux, MD
To the Editors: Martin and colleagues (1) present interesting-data, which shows significant differences among agents currently used for pharmacologic stress echocardiography with regard to their sensitivity and specificity for coronary artery disease as well as to their induction of symptoms. Unfortunately, our replication of the chi-square tests, supposedly done to test statistical significance between groups (with Yates' correction [x2y] when appropriate), does not consistently confirm the reported statistical significance. (Contact author for calculations.)
Statistical re-analysis of the data show that only 3 of 10 statistical contrasts attain their reported level of significance; 3 attain lesser degrees of statistical significance; and
Devereux RB. Pharmacologic Stress Echocardiography. Ann Intern Med. ;117:168–169. doi: 10.7326/0003-4819-117-2-168
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Published: Ann Intern Med. 1992;117(2):168-169.
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