Bruce F. Scharschmidt, MD; Michael J. Held, MA; Harry H. Hollander, MD; Alexandra E. Read, MD; Joel E. Lavine, MD, PhD; Genevieve Veereman, MD; Richard F. McGuire, MD; M. Michael Thaler, MD
Hepatitis B virus (HBV) infection is common among persons with human immunodeficiency virus (HIV) infection (1-4). Hepatitis B virus DNA is found in lymphoid cells of patients co-infected with HBV and HIV (5), and studies in cultured cells co-infected or transfected with HIV and HBV DNA indicate that the HBV X gene product enhances HIV gene expression (6, 7). These findings suggest that infection with HBV may accelerate progression of HIV-related disease, but limited clinical information is available. Therefore, we retrospectively analyzed sera from 511 HIV-infected patients for evidence of hepatitis B, in order to examine the relationship between serologic
Bruce F. Scharschmidt, Michael J. Held, Harry H. Hollander, Alexandra E. Read, Joel E. Lavine, Genevieve Veereman, et al. Hepatitis B in Patients with HIV Infection: Relationship to AIDS and Patient Survival. Ann Intern Med. 1992;117:837–838. doi: 10.7326/0003-4819-117-10-837
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Published: Ann Intern Med. 1992;117(10):837-838.
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