Fady I. Sharara, MD; George P. Chrousos, MD; Nicholas J. Patronas, MD
To the Editors: Craniopharyngiomas constitute 3% to 5% of all intracranial tumors in adults and about 15% in children. These tumors usually consist of solid cellular components and cystic areas containing oily mixtures of degenerated blood and desquamated epithelium or necrotic tissue with cholesterol crystals. Calcifications may be present in as many as 85% of cases and are detected by computed tomographic (CT) scan but not by magnetic resonance imaging (MRI) (1). Though usually slow-growing and almost always benign, they can invade various sellar and suprasellar tissues and cause significant pathology. Management has been primarily surgical, with radiation therapy as
Sharara FI, Chrousos GP, Patronas NJ. Watchful Waiting and Craniopharyngioma. Ann Intern Med. ;117:876–877. doi: 10.7326/0003-4819-117-10-876_2
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Published: Ann Intern Med. 1992;117(10):876-877.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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