Larry E. Alves, MD; Edward P. Rose, MD
To the Editors: For several years, we have used low-dose amiodarone (≤ 200 mg/d) in the treatment of patients with supraventricular arrhythmias and have seen only minimal side effects (1). Use of low-dose amiodarone has also been advocated for the treatment of congestive heart failure in patients with severely impaired left ventricular function. We use the drug to prevent sudden death in patients with complex ventricular dysrhythmias with severely impaired left ventricular function (2).
We agree with Middlekauff and colleagues that the time has come for a large-scale, long-term study in these patient groups.
They indicated that hyperthyroidism necessitated cessation
Alves LE, Rose EP. A Proposed Trial of Amiodarone for Atrial Fibrillation. Ann Intern Med. 1992;117:972–973. doi: 10.7326/0003-4819-117-11-972
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Published: Ann Intern Med. 1992;117(11):972-973.
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