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Letters |1 June 1994

Does Eating Garlic Lower Cholesterol?

Russell S. Kamer, MD; Stephen Warshafsky, MD; Steven L. Sivak, MD

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  • New York Medical College; Valhalla, NY 10595
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Drs. Lerner and Hulley mention only the null studies excluded, but most of the excluded studies favored garlic. Our objective was to study the effect of garlic on hypercholesterolemic patients, and we included trials in which most patients had cholesterol levels greater than 200 mg/dL. Most studies did not enroll patients based on cholesterol levels alone but rather on the presence of coronary artery disease, diabetes, hypertension, or hyperlipidemia of varying definitions. Thus, an arbitrary percentage cutoff was necessary. One study of 33 patients [1] showing no effect of garlic was excluded, but so was another randomized, placebo-controlled study (68 patients) that showed a 23% reduction in cholesterol levels that was associated with garlic [2].
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Kamer RS, Warshafsky S, Sivak SL. Does Eating Garlic Lower Cholesterol?. Ann Intern Med. ;120:969–970. doi: 10.7326/0003-4819-120-11-199406010-00012

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Published: Ann Intern Med. 1994;120(11):969-970.

DOI: 10.7326/0003-4819-120-11-199406010-00012

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