Skip Navigation
Menu
Original Research |15 December 1994

Cutaneous Vasculitis as the Initial Manifestation in Acute Myelomonocytic Leukemia

Konstantinos Bourantas, MD; Vasiliki D. Malamou-Mitsi, MD; Leonidas Christou, MD; Spiridoula Filippidou, RN; Alexandros A. Drosos, MD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
Copyright ©2004 by the American College of Physicians
2004
  • From the School of Medicine, University of Ioannina, Ioannina, Greece. Requests for Reprints: Alexandros A. Drosos, MD, Assistant Professor of Rheumatology, Department of Internal Medicine, School of Medicine, University of Ioannina, 451 10 Ioannina, Greece.
×
FULL TEXT
Vasculitides are a heterogeneous group of clinical disorders that are idiopathic (polyarteritis nodosa, Wegener granulomatosis) and that may be associated with connective tissue diseases (systemic lupus erythematosus, rheumatoid arthritis, scleroderma); with sepsis; or with neoplasia [1, 2], especially leukemias and lymphomas [3-11]. In vasculitides, the basic histopathologic characteristic is inflammatory changes in vessel walls. The inflammatory infiltrate can be predominantly neutrophilic (usually accompanied by leukocytoclasis), lymphocytic, or granulomatous. Necrotizing changes (usually of fibrinoid type) of the vessel wall may be present or absent. Acute myelomonocytic leukemia is a neoplastic disorder of the granulocytic and monocytic lineage that is characterized by a mixture of immature cells, mainly myeloblasts and monoblasts in the peripheral blood and bone marrow. Patients with acute myelomonocytic leukemia may present with extramedullary neoplastic infiltrates in the liver, gingiva, skin, and central nervous system. Skin involvement in acute myelomonocytic leukemia includes three types of lesions: nonspecific, leukemic cutis, and granulocytic sarcoma [12, 13].
FULL TEXT
PDF
Not Available
Citations
Citation

Bourantas K, Malamou-Mitsi VD, Christou L, Filippidou S, Drosos AA. Cutaneous Vasculitis as the Initial Manifestation in Acute Myelomonocytic Leukemia. Ann Intern Med. 1994;121:942–944. doi: 10.7326/0003-4819-121-12-199412150-00006

Download citation file:

© 2018

×
Permissions

Published: Ann Intern Med. 1994;121(12):942-944.

DOI: 10.7326/0003-4819-121-12-199412150-00006

26 Citations

Related Articles
Acute Myelomonocytic Leukemia After Cessation of Androgen Therapy
Annals of Internal Medicine; 79 (5): 749-750
View MoreView Less

Related Topics
Hematology/Oncology
Leukemia/Lymphoma
Rheumatology
Vasculitides

Hematology/Oncology, Leukemia/Lymphoma, Rheumatology, Vasculitides.

PubMed Articles
Splenectomy in patients with chronic myelomonocytic leukemia: Indications, histopathological findings and clinical outcomes in a single institutional series of 39 patients.
Am J Hematol 2018.
Making Sense of Prognostic Models in Chronic Myelomonocytic Leukemia.
Curr Hematol Malig Rep 2018.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2018 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×