Long-Term Clinical Outcomes of Lyme Disease

Mark E. McCaulley

doi:10.7326/0003-4819-122-12-199506150-00018

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TO THE EDITOR:

The recent report by Shadick and associates [1] provides valuable data on the long-term symptoms that may be found in patients with a history of Lyme borreliosis [1]. In understanding these data, however, it would be helpful to clarify the total number of symptomatic patients in both the Lyme disease and control categories. The statement that “most patients with Lyme disease in our study were without symptoms at the time of clinical assessment” [1] appears to be contradicted by the information presented in the authors' Table 3, which indicates that 61% of patients had frequent arthralgias, 26% had unusual fatigue, and 47% had trouble sleeping. It appears that of the 25 patients judged not to be persistently impaired, many were excluded because of the lack of a positive serologic test result or inadequate earlier classic manifestations, even though they met the previously stated criteria for Lyme borreliosis.

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Letters |15 June 1995

Long-Term Clinical Outcomes of Lyme Disease

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Letters |15 June 1995

Long-Term Clinical Outcomes of Lyme Disease

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