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Letters |16 July 2002

Fruit and Vegetable Intake and Coronary Heart Disease

Kaumudi J. Joshipura, ScD; Frank B. Hu, MD; Walter C. Willett, MD

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  • Harvard School of Public Health Boston, MA 02115 (Joshipura, Hu, Willett)
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IN RESPONSE:
The suggestion by Drs. Alves-Rodrigues and Thomas that the cardioprotective effect of green leafy vegetables may be related to high lutein levels is based on an animal study of lutein and arteriosclerosis (1) and a study among humans examining the relation between lutein and other antioxidants and coronary disease (2). In our study, we mentioned that antioxidant vitamins, folate, fiber, and such minerals as potassium may contribute to the apparent beneficial effects of fruits and vegetables, and we agree that lutein may also partly explain this benefit.
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Joshipura KJ, Hu FB, Willett WC. Fruit and Vegetable Intake and Coronary Heart Disease. Ann Intern Med. 2002;137:144. doi: 10.7326/0003-4819-137-2-200207160-00021

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Published: Ann Intern Med. 2002;137(2):144.

DOI: 10.7326/0003-4819-137-2-200207160-00021

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2002 American College of Physicians
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