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Letters |21 June 2011

Intensive Insulin Therapy in Hospitalized Patients

Mary Korytkowski, MD; Etie Moghissi, MD; Guillermo Umpierrez, MD

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Potential Conflicts of Interest: None disclosed.
  • From University of Pittsburgh School of Medicine, Pittsburgh, PA 15213; University of California, Los Angeles, Los Angeles, CA 90095; and Emory University School of Medicine, Atlanta, GA 30322.
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Potential Conflicts of Interest: None disclosed.
TO THE EDITOR:
Qaseem and colleagues' clinical practice guideline (1) on inpatient blood glucose level control recommends against IIT in medical and surgical patients in the hospital. This recommendation is based on a systematic review in which investigators found no consistent evidence to support strict glycemic control, defined as a target blood glucose level of 4.4 to 6.1 mmol/L (80 to 110 mg/dL) (2). The use of IIT to achieve these targets is associated with an increased risk for hypoglycemia, which is related to an increased risk for hospital complications and mortality (3).
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Korytkowski M, Moghissi E, Umpierrez G. Intensive Insulin Therapy in Hospitalized Patients. Ann Intern Med. 2011;154:846–847. doi: 10.7326/0003-4819-154-12-201106210-00021

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Published: Ann Intern Med. 2011;154(12):846-847.

DOI: 10.7326/0003-4819-154-12-201106210-00021

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