DAVID F. BROWN, M.B., B.Ch.
Idiopathic hyperlipemia is an inborn error of lipid metabolism characterized by elevated levels of serum triglyceride, cholesterol, and phospholipid. The elevated serum triglyceride level in this disorder imparts a milky appearance to the serum even in the fasting state and differentiates it from the closely allied familial disorder, idiopathic hypercholesterolemia. Patients with idiopathic hyperlipemia frequently exhibit xanthomatous deposits in skin and tendons. They are prone to develop attacks of acute pancreatitis, mild diabetes is common, and the liver and spleen may be enlarged. While the condition was initially regarded as benign, this view is no longer tenable following recognition that
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BROWN DF. IDIOPATHIC HYPERLIPEMIA AND ISCHEMIC HEART DISEASE(IDIOPATHIC HYPERLIPEMIA AND ISCHEMIC HEART DISEASE*†)(IDIOPATHIC HYPERLIPEMIA AND ISCHEMIC HEART DISEASE*†). Ann Intern Med. 1961;54:646–659. doi: 10.7326/0003-4819-54-4-646
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Published: Ann Intern Med. 1961;54(4):646-659.
Cardiology, Coronary Heart Disease, Coronary Risk Factors, Dyslipidemia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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