Erin S. LeBlanc, MD, MPH; Elizabeth O'Connor, PhD
Potential Conflicts of Interest: Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M11-0823.
LeBlanc E., O'Connor E.; Effectiveness of Primary Care–Relevant Treatments for Obesity in Adults. Ann Intern Med. 2012;156:249. doi: 10.7326/0003-4819-156-3-201202070-00020
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Published: Ann Intern Med. 2012;156(3):249.
We thank Dr. Kuller for his comments. We conducted this systematic review for the USPSTF to make its recommendation about screening and treatment of adult obesity. The USPSTF recently posted a draft recommendation for public comment but has not released its final recommendation.
With regard to the articles in question, we excluded the Look AHEAD and WOMAN studies because the control groups received more than a minimal intervention, which was outside the focus of our review. Our systematic review summarized the data regarding the effectiveness of weight loss interventions compared with no intervention or usual care. We also excluded the 10-year DPP data from our review because they were derived from a cohort design. The long-term weight loss data in the intervention groups outlined by Dr. Kuller are consistent with our review. In those same studies, the control groups lost minimal to no weight or gained weight (nearly 2 kg in the TOHP, phase 2, and Hypertension Prevention Trial). Therefore, when pooled, the amount of weight loss in the intervention groups was statistically significantly greater than that in the control groups.
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