Katrin Uhlig, MD, MS; Andrew S. Levey, MD
Katrin Uhlig, MD, MS
Andrew S. Levey, MD
Tufts Medical Center
Boston, MA 02111
Acknowledgment: Aghogho Okparavero, MD, provided assistance with the manuscript.
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M12-0413.
Corresponding Author: Andrew S. Levey, MD, Tufts Medical Center, Box 391, 800 Washington Street, Boston, MA 02111; e-mail, mailto:email@example.com.
Current Author Addresses: Drs. Uhlig and Levey: Tufts Medical Center, Box 391, 800 Washington Street, Boston, MA 02111.
Uhlig K., Levey A.; Developing Guidelines for Chronic Kidney Disease: We Should Include All of the Outcomes. Ann Intern Med. 2012;156:599-601. doi: 10.7326/0003-4819-156-8-201204170-00012
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Published: Ann Intern Med. 2012;156(8):599-601.
This year marks the 10-year anniversary of the publication of the initial Kidney Disease Outcomes Quality Initiative guidelines for chronic kidney disease (CKD) (1). These guidelines have been accepted internationally with minor modification (2) and have led to worldwide recognition of CKD as a public health problem (3). The guidelines define and stage CKD on the basis of glomerular filtration rate (GFR) estimated from serum creatinine as a measure of kidney function and albuminuria as a marker of kidney damage, regardless of the underlying cause. This simple definition and staging system enabled detection of CKD by nonnephrologists and identification of a high prevalence of earlier CKD stages in adults (11% in the United States), which can often be cared for by generalists, in contrast to a low prevalence of advanced stages (1%), which require nephrologist care (4). The guidelines fostered the implementation of automated reporting of estimated GFR by laboratories when serum creatinine is measured and encouraged more frequent testing for albuminuria (5).
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Nephrology, Hypertension, Chronic Kidney Disease, Prevention/Screening.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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