Charles M. Rubin, MD
Rubin C.; The Genetic Basis of Human Cancer. Ann Intern Med. 1998;129:759. doi: 10.7326/0003-4819-129-9-199811010-00045
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Published: Ann Intern Med. 1998;129(9):759.
The Genetic Basis of Human Cancer; Vogelstein B, Kinzler KW; eds. 731 pages. New York: McGraw-Hill; 1998. $95.00. ISBN 0070675961. Order phone 800-262-4729.
Field of medicine: Cancer biology, oncology, and genetics.
Format: Hardcover book.
Audience: Scientists in cancer research, medical and graduate students, oncologists, and geneticists.
Purpose: To describe the role of genes in the development of cancer.
Content: This text has 43 chapters grouped into four parts: basic concepts in cancer genetics, control of solid-growth tumors, familial cancer syndromes, and site-specific neoplasms. The first chapter serves as a primer in human genetics that can be used as a reference for the rest of the book. The book attempts to answer several questions: Which cancers have a clear genetic component? What genes are involved? What is the nature of the mutations in these genes? How do these genes work? What are the implications of knowledge about genes for diagnosis and future treatment?
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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