Francesco P. Cappuccio, MD, DSc; Michelle A. Miller, PhD
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M12-2146.
Requests for Single Reprints: Francesco P. Cappuccio, MD, DSc, University of Warwick, Warwick Medical School, University Hospitals Coventry and Warwickshire Campus, Clifford Bridge Road, Coventry CV2 2DX, United Kingdom; e-mail, firstname.lastname@example.org.
Current Author Addresses: Drs. Cappuccio and Miller: University of Warwick, Warwick Medical School, University Hospitals Coventry and Warwickshire Campus, Clifford Bridge Road, Coventry CV2 2DX, United Kingdom.
Cappuccio FP, Miller MA. A New Challenge to Widely Held Views on the Role of Sleep. Ann Intern Med. 2012;157:593-594. doi: 10.7326/0003-4819-157-8-201210160-00016
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Published: Ann Intern Med. 2012;157(8):593-594.
Philosophers, moralists, and scientists have been interested in sleep since ancient times. Although hypotheses and beliefs about the role of sleep have varied over the centuries, many have considered sleep to be an idle state or a sole function of the brain (1). However, suggestions of a link between sleep and metabolic functions can be found in early Roman medicine. Aulus Cornelius Celsus (circa 25 BCE to 50 ACE) argued in favor of “restricted sleep” for the treatment of extra weight, and Galen (129 to circa 216 ACE) listed “somnux et vigilia” (sleeping and waking) as important causes of illness (2).
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