Harvey G. Klein, MD; Charles Natanson, MD
Potential Conflicts of Interest: None disclosed.
Klein HG, Natanson C. Red Blood Cell Transfusion. Ann Intern Med. 2012;157:753-754. doi: 10.7326/0003-4819-157-10-201211200-00019
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Published: Ann Intern Med. 2012;157(10):753-754.
TO THE EDITOR:
Carson and colleagues' guideline (1) for the AABB of adhering to a “restrictive” transfusion threshold that relies on a hemoglobin level of 7 to 8 g/dL or less for hemodynamically stable patients is well-intentioned but problematic. We are not surprised that the editorial (2) accompanying this proposed guideline arrives at a different conclusion—one that we agree with. We also believe that transfusion thresholds should be titrated on the basis of many important individual patient laboratory and physiologic variables. Why the disparity after considering the same decade of clinical experience and trial data? The weaknesses of the most influential trial are well-described in the editorial.
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