Peter S. Hussey, PhD; Samuel Wertheimer, MPH; Ateev Mehrotra, MD, MPH
Disclaimer: Dr. Hussey had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Grant Support: By grant 68339 from the Robert Wood Johnson Foundation.
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M11-2757.
Requests for Single Reprints: Peter S. Hussey, PhD, RAND, 1200 South Hayes Street, W7W, Arlington, VA 22202; e-mail, firstname.lastname@example.org.
Current Author Addresses: Dr. Hussey: RAND, 1200 South Hayes Street, W7W, Arlington, VA 22202.
Dr. Wertheimer: Harvard Business School, Soldiers Field, Boston, MA 02163.
Dr. Mehrotra: RAND, 4570 Fifth Avenue, Suite 600, Pittsburgh, PA 15213.
Author Contributions: Conception and design: P.S. Hussey, A. Mehrotra.
Analysis and interpretation of the data: P.S. Hussey, S. Wertheimer, A. Mehrotra.
Drafting of the article: P.S. Hussey, S. Wertheimer.
Critical revision of the article for important intellectual content: P.S. Hussey, A. Mehrotra.
Final approval of the article: P.S. Hussey, A. Mehrotra.
Statistical expertise: P.S. Hussey.
Obtaining of funding: P.S. Hussey, A. Mehrotra.
Administrative, technical, or logistic support: P.S. Hussey, S. Wertheimer.
Collection and assembly of data: P.S. Hussey, S. Wertheimer.
Although there is broad policy consensus that both cost containment and quality improvement are critical, the association between costs and quality is poorly understood.
To systematically review evidence of the association between health care quality and cost.
Electronic literature search of PubMed, EconLit, and EMBASE databases for U.S.-based studies published between 1990 and 2012.
Title, abstract, and full-text review to identify relevant studies.
Two reviewers independently abstracted data with differences reconciled by consensus. Studies were categorized by level of analysis, type of quality measure, type of cost measure, and method of addressing confounders.
Of 61 included studies, 21 (34%) reported a positive or mixed-positive association (higher cost associated with higher quality); 18 (30%) reported a negative or mixed-negative association; and 22 (36%) reported no difference, an imprecise or indeterminate association, or a mixed association. The associations were of low to moderate clinical significance in many studies. Of 9 studies using instrumental variables analysis to address confounding by unobserved patient health status, 7 (78%) reported a positive association, but other characteristics of these studies may have affected their findings.
Studies used widely heterogeneous methods and measures. The review is limited by the quality of underlying studies.
Evidence of the direction of association between health care cost and quality is inconsistent. Most studies have found that the association between cost and quality is small to moderate, regardless of whether the direction is positive or negative. Future studies should focus on what types of spending are most effective in improving quality and what types of spending represent waste.
Robert Wood Johnson Foundation.
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Hussey PS, Wertheimer S, Mehrotra A. The Association Between Health Care Quality and Cost: A Systematic Review. Ann Intern Med. 2013;158:27–34. doi: 10.7326/0003-4819-158-1-201301010-00006
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Published: Ann Intern Med. 2013;158(1):27-34.
Healthcare Delivery and Policy, High Value Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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