Francine Grodstein, ScD (*); Jacqueline O’Brien, ScD (*); Jae Hee Kang, ScD; Rimma Dushkes, PhD; Nancy R. Cook, ScD; Olivia Okereke, MD; JoAnn E. Manson, MD, DrPH; Robert J. Glynn, PhD; Julie E. Buring, ScD; J. Michael Gaziano, MD, MPH; Howard D. Sesso, ScD, MPH
* Drs. Grodstein and O’Brien contributed equally to this work.
Acknowledgment: The authors thank the 14 641 physician participants for their long-standing dedication and conscientious collaboration; the long-term contributions of Charles Hennekens, MD, DrPH, Florida Atlantic University, to the Physicians’ Health Study; and the exemplary contributions of the staff of the Physicians’ Health Study at Brigham and Women's Hospital.
Grant Support: By grants CA 097193, CA 34944, CA 40360, HL 26490, HL 34595, AG 15933, and T32-AG000158 from the National Institutes of Health, and an investigator-initiated grant from BASF. Study agents and packaging were provided by BASF and Pfizer, and study packaging was provided by DSM Nutritional Products.
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-1340.
Reproducible Research Statement: Study protocol: Available from Drs. Sesso (email@example.com) and Gaziano (firstname.lastname@example.org). Statistical code: Not available. Data set: Not available.
Requests for Single Reprints: Francine Grodstein, ScD, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115; e-mail, email@example.com.
Current Author Addresses: Drs. Grodstein, O’Brien, Kang, Dushkes, Cook, Orereke, Manson, Glynn, Buring, Gaziano, and Sesso: Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115.
Author Contributions: Conception and design: F. Grodstein, J.E. Manson, R.J. Glynn, J.E. Buring, J.M. Gaziano.
Analysis and interpretation of the data: F. Grodstein, J. O’Brien, J.H. Kang, R. Dushkes, N.R. Cook, O. Okereke, J.E. Manson, R.J. Glynn, J.M. Gaziano, H.D. Sesso.
Drafting of the article: J. O’Brien, J.E. Buring.
Critical revision of the article for important intellectual content: F. Grodstein, J. O’Brien, J.H. Kang, R. Dushkes, N.R. Cook, O. Okereke, J.E. Manson, R.J. Glynn, J.E. Buring, J.M. Gaziano, H.D. Sesso.
Final approval of the article: F. Grodstein, J. O’Brien, J.H. Kang, R. Dushkes, N.R. Cook, O. Okereke, J.E. Manson, R.J. Glynn, J.E. Buring, J.M. Gaziano, H.D. Sesso.
Provision of study materials or patients: J.M. Gaziano, H.D. Sesso.
Statistical expertise: F. Grodstein, J.H. Kang, N.R. Cook, R.J. Glynn.
Obtaining of funding: F. Grodstein, J.M. Gaziano, H.D. Sesso.
Administrative, technical, or logistic support: F. Grodstein, J.M. Gaziano, H.D. Sesso.
Collection and assembly of data: F. Grodstein, J.E. Buring, J.M. Gaziano.
Grodstein F, O’Brien J, Kang JH, Dushkes R, Cook NR, Okereke O, et al. Long-Term Multivitamin Supplementation and Cognitive Function in Men: A Randomized Trial. Ann Intern Med. 2013;159:806-814. doi: 10.7326/0003-4819-159-12-201312170-00006
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Published: Ann Intern Med. 2013;159(12):806-814.
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