Jean-Philippe Chaput, PhD; Arya M. Sharma, MD, PhD
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0020.
Chaput J, Sharma AM. Metabolically Healthy Overweight and Obesity. Ann Intern Med. 2014;160:513. doi: 10.7326/L14-5007
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Published: Ann Intern Med. 2014;160(7):513.
Kramer and colleagues (1) conclude that “there is no healthy pattern of increased weight.” However, all of the studies included in this analysis define unhealthy obesity as the presence of at least 2 components of the metabolic syndrome. Thus, by definition, persons with just 1 risk factor (such as hypertension, elevated fasting glucose levels, or hypercholesterolemia) would be considered “metabolically healthy.” It is not surprising that this group has an elevated risk for cardiovascular events. We believe that this meta-analysis adds to the confusion on the topic by defining “healthy obesity” by criteria that we would consider anything but healthy.
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