Michael L. LeFevre, MD, MSPH; on behalf of the U.S. Preventive Services Task Force (*)
Disclaimer: Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
Financial Support: The USPSTF is an independent, voluntary body. The U.S. Congress mandates that the Agency for Healthcare Research and Quality support the operations of the USPSTF.
Disclosures: Dr. Owens reports support from the Agency for Healthcare Research and Quality during the conduct of the study. Authors not named here have disclosed no conflicts of interest. Authors followed the policy regarding conflicts of interest described at www.uspreventive servicestaskforce.org/methods.htm. Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-1018.
Requests for Single Reprints: Reprints are available from the USPSTF Web site (www.uspreventiveservicestaskforce.org).
LeFevre ML, on behalf of the U.S. Preventive Services Task Force. Screening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med. 2014;161:58-66. doi: 10.7326/M14-1018
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Published: Ann Intern Med. 2014;161(1):58-66.
Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for hepatitis B virus (HBV) infection.
The USPSTF reviewed the evidence on the benefits and harms of antiviral treatment, the benefits of education or behavior change counseling, and the association between improvements in intermediate and clinical outcomes after antiviral therapy.
This recommendation applies to asymptomatic, nonpregnant adolescents and adults at high risk for HBV infection (including those at high risk who were vaccinated before being screened for HBV infection).
The USPSTF concludes that persons at high risk for infection should be screened for HBV infection. (B recommendation)
Screening for hepatitis B virus infection in nonpregnant adolescents and adults: clinical summary of U.S. Preventive Services Task Force recommendation.
Appendix Table 1. What the USPSTF Grades Mean and Suggestions for Practice
Appendix Table 2. USPSTF Levels of Certainty Regarding Net Benefit
Table 1. Geographic Regions With a Prevalence of Hepatitis B Surface Antigen ≥2%*
Prevalence of hepatitis B surface antigen in adults aged 19 to 49 years, 2005.
Reproduced with permission of Elsevier from reference 5.
Table 2. Prevalence of HBV Infection, by Risk Group
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Gastroenterology/Hepatology, Guidelines, Infectious Disease, Prevention/Screening, Viral Hepatitis.
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