Balz Frei, PhD; Bruce N. Ames, PhD; Jeffrey B. Blumberg, PhD; Walter C. Willett, MD, DrPH
Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0076.
Frei B., Ames B., Blumberg J., Willett W.; Enough Is Enough. Ann Intern Med. 2014;160:807. doi: 10.7326/L14-5011
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Published: Ann Intern Med. 2014;160(11):807.
Guallar and colleagues (1) conclude that “the case is closed—supplementing the diet of well-nourished adults with (most) mineral or vitamin supplements has no clear benefit and might even be harmful.” However, they ignore decades of nutrition research and diet monitoring of the U.S. population to reach this misleading conclusion.
Although a well-balanced diet is the best way to get essential nutrients (except vitamin D and, for vegans and many older adults, vitamin B12), few persons in the United States follow the Dietary Guidelines for Americans. Consequently, most persons in the United States are not “well-nourished” and do not meet the Institute of Medicine's recommendations for the dietary intake of all vitamins and essential minerals.
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