Irvine Mason, MD
Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0080.
Mason I.; Enough Is Enough. Ann Intern Med. 2014;160:808. doi: 10.7326/L14-5011-2
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Published: Ann Intern Med. 2014;160(11):808.
Guallar and colleagues (1) purport that their opinions are facts. They state that most supplements “do not prevent chronic disease or death ... and they should be avoided.”
The authors totally disregard the best and most comprehensive study to date, PHS II (2). This study followed nearly 15 000 male physicians aged 50 years or older for up to 13 years. It revealed that use of a Centrum Silver (Pfizer, New York, New York) multivitamin alone reduced the risk for cancer in men from any source by 8%. The study also found that multivitamin use decreased site-specific cancer (except for prostate cancer) by 12% and suggested a 12% reduction in deaths caused by cancer.
William M. Fogarty, Jr., MD, FACP
St. Louis University School of Medicine
June 2, 2014
Letter by Irvine Mason
Dr. Mason's last paragraph calling the author of the article being questioned is inappropriate in the Annals or any other serious medical journal. His letter should be removed from the Annals.
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