Jessica Fargnoli, MPH; Joyce Greenleaf, MBA; Melissa Hafner, MPP
Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0077.
Fargnoli J, Greenleaf J, Hafner M. Enough Is Enough. Ann Intern Med. 2014;160:809. doi: 10.7326/L14-5011-5
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Published: Ann Intern Med. 2014;160(11):809.
Guallar and colleagues (1) draw attention to mounting evidence that most vitamin and mineral supplements do not prevent chronic diseases and in some cases may be harmful. We share the authors' concerns and have released 2 related reports (2, 3) that further highlight risks of dietary supplements based on our review of their labels. Manufacturers make claims on these labels that the U.S. Food and Drug Administration (FDA) has limited authority to review; however, consumers rely on those claims in purchasing supplements.
In the first report, we found that claims made on dietary supplement labels may be misleading. Specifically, we reviewed the substantiation for structure/function claims found in a sample of supplements marketed for weight loss and immune support. The FDA requires that supplement manufacturers have substantiation to support such claims on their products' labels and has issued guidance on the scientific support necessary to do so.
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