Cheryl Bushnell, MD, MHS; Louise McCullough, MD, PhD
Financial Support: Dr. Bushnell is supported the Hazel K. Goddess Fund for Stroke Research in Women and the World Federation of Neurology. Dr. McCullough is supported by grants RO1 NS055215, RO1 NS077769, and R21 NS082906 from the National Institutes of Health.
Disclosures: Dr. McCullough reports personal fees from Genentech outside the submitted work. Authors not named here have disclosed no conflicts of interest. Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-0762.
Requests for Single Reprints: Cheryl Bushnell, MD, MHS, Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157; e-mail, firstname.lastname@example.org.
Current Author Addresses: Dr. Bushnell: Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157.
Dr. McCullough: Department of Neurology, University of Connecticut Health Center, 263 Farmington Avenue, Suite MC1840, Farmington, CT 06032.
Author Contributions: Conception and design: C. Bushnell.
Drafting of the article: C. Bushnell, L. McCullough.
Critical revision of the article for important intellectual content: C. Bushnell, L. McCullough.
Final approval of the article: C. Bushnell, L. McCullough.
Collection and assembly of data: L. McCullough.
Bushnell C, McCullough L. Stroke Prevention in Women: Synopsis of the 2014 American Heart Association/American Stroke Association Guideline. Ann Intern Med. 2014;160:853-857. doi: 10.7326/M14-0762
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Published: Ann Intern Med. 2014;160(12):853-857.
In February 2014, the American Heart Association/American Stroke Association released their first guideline focused on stroke prevention in women. This new guideline highlights unique risk factors for stroke in women, including oral contraception and hormone therapy, and pregnancy-associated disorders, such as preeclampsia, that may have long-lasting consequences on a woman's health. It also addresses hypertension; atrial fibrillation; migraine headache with aura; and the epidemiology of types of stroke, such as aneurysmal subarachnoid hemorrhage and cerebral vein thrombosis, that are predominant in women.
Members of a multidisciplinary expert panel searched, reviewed, and critiqued relevant English-language literature published between 1990 and May 2013. The panel devised evidence tables and developed recommendations using American Heart Association guideline procedures and levels of evidence.
This synopsis of the guideline summarizes the evidence about risk factors for stroke in women and suggests prevention strategies. It also describes the new recommendations relevant to identifying and treating hypertensive disorders in pregnancy that increase risk for stroke.
Table. Risk Factors for Stroke
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