Tomoe Hayashi, MD, PhD; Noriharu Nakagawa, MD; Yasuko Kadohira, MD; Eriko Morishita, MD, PhD; Hidesaku Asakura, MD, PhD
Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0131.
Hayashi T, Nakagawa N, Kadohira Y, Morishita E, Asakura H. Rivaroxaban in a Patient With Disseminated Intravascular Coagulation Associated With an Aortic Aneurysm: A Case Report. Ann Intern Med. 2014;161:158-159. doi: 10.7326/L14-5014-3
Download citation file:
Published: Ann Intern Med. 2014;161(2):158-159.
Background: Progressive disseminated intravascular coagulation (DIC) causes bleeding due to consumption coagulopathy and excessive fibrinolytic activation and organ failure due to microcirculatory dysfunction (1). Disseminated intravascular coagulation associated with aortic aneurysms is characterized by marked fibrinolytic activation (2). When severe bleeding develops, DIC has conventionally been treated with a continuous heparin infusion (3), but the restrictions on patients are great and continuous intravenous infusion is problematic for outpatient care. Patient-administered subcutaneous heparin injections with a longer half-life are frequently selected (4), but the treatment burden remains high.
Learn more about subscription options.
Register Now for a free account.
Results provided by:
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only