Brian Budenholzer, MD
Budenholzer B.; Review: In high-risk patients, fatty acid supplementation does not prevent coronary events. Ann Intern Med. 2014;161:JC7. doi: 10.7326/0003-4819-161-6-201409160-02007
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Published: Ann Intern Med. 2014;161(6):JC7.
Bangladesh Institute of Family Medicine and Research
September 16, 2014
No cardiovascular benefit? Still Omega-3 fatty acids should not be ignored.
Whether high level of serum triglyceride is a direct cardiovascular risk factor is still a debate but as a component of metabolic syndrome hypertriglyceridemia is a cardiovascular risk factor. On the other hand high triglyceride frequently is associated with low HDL-C and high LDL-C named as atherogenic dyslipidemia which is also a cardiovascular risk factor.This meta-analysis proved that supplementation of none of Omega-3, Omega-6 and ALA prevented cardiovascular event but as a clinical person, we need to reduce triglyceride level down to <150mg/dl. In July 2012, FDA has introduced high dose EPA only (vascepa) capsule for the management of very high triglyceride.Cardiac arrhythmia is common in patients with cardiometabolic disease like diabetes and hypertension and is one of the causes of sudden cardiac death (SCD). Omega-3 fatty acids are found to prevent cardiac arrhythmia.Statins are found to reduce both cardiovascular and all cause mortality and prescription of statin has been increased dramatically as a result of 2013 ACC/AHA dyslipidemia guideline. What is wrong if we prescribe fish oil supplement along with statin in patients with atherogenic dyslipidemia?
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Cardiology, Coronary Risk Factors, Coronary Heart Disease, Prevention/Screening.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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