Kasia J. Lipska, MD, MHS; Victor M. Montori, MD
Lipska K., Montori V.; In type 1 diabetes, intensive insulin therapy for 6.5 y reduced mortality at 27 y compared with usual care. Ann Intern Med. 2015;162:JC12. doi: 10.7326/ACPJC-2015-162-10-012
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Published: Ann Intern Med. 2015;162(10):JC12.
Bangladesh Institute of Family Medicine and Research
August 6, 2015
Tight glycemic control in young diabetes patients is beneficial and less risky
Take home message of this trial is that that a physician should go for intensive insulin therapy to achieve intensive glycemic control in young type 1 diabetes patients. Although intensive glycemic control is always beneficial in terms of both micro and macrovascular complications in both type 1 and type 2 diabetes patients but to achieve close to euglycemic state is risky in patients with longer duration of hyperglycemia and associated comorbid conditions. This population is extremely vulnerable to hypoglycemia and even hypoglycemia unawareness which may lead a patient directly to neuroglycopenia without having alarming sympatho-adrenal symptoms. What I observed that exclusion criteria of this study are duration of hyperglycemia equal or more than 15-years and significant albuminuria. This means that it is highly beneficial to achieve glycemic control close to normoglycemic individuals to prevent micro and macrovascular adverse effects in young diabetic patients specifically soon after diagnosis.
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Cardiology, Endocrine and Metabolism, Diabetes, Coronary Risk Factors.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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