Janelle M. Guirguis-Blake, MD; Tracy L. Beil, MS; Evelyn P. Whitlock, MD, MPH
Guirguis-Blake JM, Beil TL, Whitlock EP. Correction: Ultrasonography Screening for Abdominal Aortic Aneurysms. Ann Intern Med. 2016;164:70-72. doi: 10.7326/L160010
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Published: Ann Intern Med. 2016;164(1):70-72.
TO THE EDITOR:
In our article, “Ultrasound Screening for Abdominal Aortic Aneurysms: A Systematic Evidence Review for the U.S. Preventive Services Task Force” (1), we state that neither the individual population-based abdominal aortic aneurysm (AAA) screening trials, nor our pooled analysis of these trials, showed a statistically significant reduction in all-cause mortality. However, a careful reader, Frank Lederle, pointed out that the authors of MASS (Multicentre Aneurysm Screening Study), a large, good-quality trial, reported their hazard ratio (HR) for all-cause mortality to be statistically significant at 13-year follow-up (HR, 0.97 [95% CI, 0.95 to 0.99]) (2); these data are shown in Table 2 of the manuscript and seem to contradict our statement. Dr. Lederle also questioned whether pooled results for all-cause mortality with upper CIs of 1.00 may in some cases be statistically significant if carried to 3 decimal places. We would like to walk Annals readers through these issues and our series of analyses to clarify what may appear to be discrepancies in our results and conclusions.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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