Ebrahim Barkoudah, MD, MPH; Larry A. Weinrauch, MD
Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterest Forms.do?msNum=L16-0100.
Barkoudah E, Weinrauch LA. Screening for Abnormal Blood Glucose and Type 2 Diabetes Mellitus. Ann Intern Med. 2016;165:225. doi: 10.7326/L16-0100
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Published: Ann Intern Med. 2016;165(3):225.
TO THE EDITOR:
We read with interest the U.S. Preventive Services Task Force's recommendation on screening asymptomatic adults in primary care settings for diabetes (1). Although the focus on hard events in clinical trials is understandable and appropriate, the authors do not fully examine why they discounted morbid events when producing this guideline. Focusing on all-cause mortality in patients at low risk for death and for a short time is insufficient to draw conclusions when mortality rates are low (2). Therefore, a finding of clinical equipoise may represent a statistical error because the studies are underpowered to define a difference among strategies.
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