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The author reports a case of infantile, constitutional anemia, pernicious in character, occurring in a boy of 6 years. The cause of the anemia was regarded as the result of a quantitative underdevelopment of the red bone-marrow, without change of bony structure. The blood-forming marrow present was completely capable of functioning, but its total mass was greatly reduced. This red blood cell-forming marrow was limited to the shaft and upper diaphysis of the femur, and to small islands in the vertebrae. All other marrow spaces were filled with fatty tissue only (lipomatosis ex vacuo). The bony substance was neither increased
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Constitutional Infantile (Pernicious-like) Anemia.. Ann Intern Med. 1929;3:390-391. doi: 10.7326/0003-4819-3-4-390
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Published: Ann Intern Med. 1929;3(4):390-391.
Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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