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The sudden release of bile obtained by incising the gall bladder of a decerebrated or ether-anesthetized frog is almost invariably attended by an abrupt change in the rate and character of beating of the heart. The first event is a transient arrest of the entire heart lasting between 1 and 10 seconds, almost always followed by a sinus bradycardia lasting from one-half to ten minutes. Subsequently there is a return to the initial rate of beating, although in a few instances progressive slowing, leading to excessive dilation and permanent arrest, have been observed. Not infrequently the first event to be
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Reflexes from the Gall bladder to the Heart.. Ann Intern Med. 1930;3:1165. doi: 10.7326/0003-4819-3-11-1165_1
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Published: Ann Intern Med. 1930;3(11):1165.
Biliary Disorders, Cardiology, Gastroenterology/Hepatology, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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