JOHN C. KRANTZ JR., Ph.D.; A. A. SILVER, M.D.; BERNARD J. HOFFMAN
In a previous communication to this journal, one of us (J.K.) (1) studied the metabolism of a certain sodium malate mixture when employed as a dietary substitute for sodium chloride. The mixture studied consisted of 85.5 per cent of disodium malate, 9 per cent of trisodium citrate, 5 per cent of triammonium citrate and 0.5 per cent of manganese bromide. In this work the administration of this mixture of salts in the form of a condiment was shown to influence the acid-base equilibrium of the urine in the direction of the alkaline side. The malic acid was apparently completely metabolized.
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KRANTZ JC, SILVER AA, HOFFMAN BJ. The Effect of Sodium Malate Combinations Upon Gastric Acidity. Ann Intern Med. 1931;4:1441–1446. doi: 10.7326/0003-4819-4-11-1441
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Published: Ann Intern Med. 1931;4(11):1441-1446.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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